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doi: 10.3389/fendo.2025.1573526 Received 09 February 2025 Accepted 15 September 2025 Published 01 October 2025 Volume 16 - 2025 Edited by Claus Yding Andersen, University of Copenhagen, Denmark Reviewed by Gennaro Lettieri, University of Naples Federico II, Italy Anitha Myla, Mississippi State Department of Health, United States Updates Copyright 2025 Han and Jin

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Conceptual convergence: increased inflammation is associated with increased basal ganglia glutamate in patients with major depression

Investigating these genes in greater detail allows researchers to deepen their understanding of the genetic architecture of depression and to identify potential biomarkers for personalized treatment strategies